TCDD.Transcriptomics is a datasets package for R that contains standardized data from numerous studies into TCDD-mediated responses of the mammalian transcriptomic landscape. Specifically, the TCDD.Transcriptomics package contains data fr om 49 separate experiments encompassing 3 mammalian species (human, rat and mouse) including multiple strains of rat and mouse, 4 tissue types (liver, hypothalamus, adipose and kidney) and a large number of doses and time points following exposure. This package provides access to both normalized RNA abundance data as well as results from linear modeling, providing the magnitude and significance of change relative to controls, as well as extensive sample annotation.


  • R (>= 3.0.2)
  • BPG


To install in an interactive R session, do the following:
install.packages("TCDD.Transcriptomics", type="source", repos = "")
This will install TCDD.Transcriptomics and it's dependencies from our miniCRAN repository.

Mac users will need to do the following before installing the package in R:
  • Ensure that your Xcode license is accepted with the following command:
    sudo xcodebuild --license
  • If fortran is not installed, install it with the following commands:
    curl -O
    sudo tar fvxz gfortran-4.8.2-darwin13.tar.bz2 -C /
  • Set up your active developer directory for Xcode and BSD tools:
    xcode-select --install


A detailed description of all functions and their parameters can be found in the API.


Version 2.1.1
(104.3 MB)