Germline Filter is a Python program used in the ICGC-TCGA DREAM Mutation Calling Challenge meant to contribute to the real data security measures. It takes as input a preprocessed and encrypted germline calls file, as generated by GATK, and a somatic SNV vcf file, and it returns the number of germline calls found in the somatic vcf.


GermlineFilter is availble as a Python package from the following link: